The 24-hour service on route 365 will provide valuable night time links for residents of Havering
The route, which runs between the Mardyke Estate and Havering Park, will run every half hour between 00.30 and 05.00 every night of the week.
The changes will bring night time bus services to South Hornchurch for the first time and provide links to Romford and Collier Row.
John Barry, Head of Network Development, London Buses, said: 'The 24-hour service on route 365 will provide valuable night time links for residents of Havering and is an important addition to London's expanding night bus network.'
The number of night bus services in London has increased significantly in recent years with passenger numbers more than doubling since 2000.
Almost half the users are people travelling to or from work.
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